3D and 4D NMR Service for Large Biomolecules Based on 700 MHz Spectrometer

STEMart provides advanced 3D and 4D NMR services for large biomolecules using high-performance 700 MHz spectrometers, including the Bruker Avance III 700 MHz and Bruker Avance NEO 700 MHz systems with Cryoprobe technology. These instruments are specially designed for high-resolution multidimensional NMR studies, allowing us to analyze complex biomolecules like proteins, nucleic acids, and large peptides. Our 3D and 4D NMR services enable researchers to obtain detailed structural information, supporting fields such as structural biology, biochemistry, and drug discovery.

3D and 4D NMR spectroscopy are powerful techniques that extend beyond traditional 1D and 2D NMR, enabling the separation of overlapping signals and providing in-depth insights into biomolecular structures and interactions. By introducing additional frequency dimensions, these techniques offer high-resolution data that reveal long-range correlations and intricate structural relationships. This service is widely used to elucidate biomolecular folding, binding sites, and dynamic behaviors, essential for understanding biological function and designing targeted therapeutics.

Leveraging our advanced 700 MHz spectrometers, STEMart offers a comprehensive range of multidimensional NMR services, including structural determination, resonance assignment, and molecular dynamics studies. Our services provide researchers with detailed and accurate data necessary for advancing biomolecular research and optimizing drug design and development.

What We Offer

• Resonance Assignment for Large Biomolecules

Uses 3D and 4D NMR to achieve precise resonance assignments, supporting detailed structural analysis of complex biomolecules.

• Structural Determination of Proteins and Nucleic Acids

Provides comprehensive 3D and 4D NMR data to determine the full structure of proteins and nucleic acids, essential for understanding function.

• Molecular Dynamics and Flexibility Studies

Analyzes biomolecular dynamics to reveal flexible regions, supporting research into molecular mechanisms and stability.

• Binding Site Identification and Analysis

Detects binding sites on large biomolecules, crucial for drug discovery and molecular interaction studies.

Why Choose Us

• High-Resolution and Sensitivity for Large Biomolecules

Our 700 MHz spectrometers are optimized for 3D and 4D NMR, providing high resolution and sensitivity for accurate biomolecular analysis.

• Experienced Biomolecular NMR Team

Our specialists have extensive experience with multidimensional NMR, ensuring precise data interpretation and supporting complex structural studies.

• Comprehensive Data and Custom Reports

We offer customized, detailed reports tailored to specific research needs, ensuring clarity and actionable insights.

• Non-Destructive Analysis

Our NMR techniques preserve sample integrity, allowing further testing and analysis as needed, especially valuable for limited or precious samples.

Our Resources

Bruker Avance III 700 MHz NMR

This Bruker 700 MHz spectrometer features high sensitivity and Cryoprobe technology, allowing for precise 3D and 4D NMR studies. Its advanced capabilities make it ideal for structural determination and dynamic studies of large biomolecules, supporting research in structural biology and biochemistry.

Bruker Avance NEO 700 MHz NMR with Cryoprobe

The Bruker Avance NEO 700 MHz system offers enhanced resolution and sensitivity for multidimensional NMR, making it a powerful tool for analyzing large biomolecular structures. Equipped with Cryoprobe technology, it provides reliable data for resonance assignment, structural elucidation, and biomolecular interaction studies.

STEMart provides high-quality NMR services tailored to meet the specific needs of our clients. Our experienced specialists use advanced equipment and follow strict quality control measures to ensure accurate and reliable results. Contact us to learn more about our NMR services and how we can help you achieve your research goals.