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Prostate-specific antigen, or PSA, is a protein produced by normal, as well as malignant, cells of the prostate gland. The blood level of PSA is often elevated in people with prostate cancer, and the PSA test was originally approved+E71 in 1986 to monitor the progression of prostate cancer in men who had already been diagnosed with the disease. PSA testing (along with a DRE) is also often used by health care providers for individuals who report prostate symptoms to help determine the nature of the problem. In addition to prostate cancer, several benign (not cancerous) conditions can cause a person’s PSA level to rise, particularly prostatitis (inflammation of the prostate) and benign prostatic hyperplasia (BPH) (enlargement of the prostate). M612166 is the 100% PSA Monoclonal Antibody.