Analysis of ARID4B Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0254-LGZ)

Introduction

Official Full Name: AT-rich interaction domain 4B<br />Also known as: BCAA; BRCAA1; RBP1L1; SAP180; RBBP1L1<br />The protein sequence encoded by this gene is similar to retinoblastoma binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependent SIN3A transcriptional co-repressor complex that functions in a variety of cellular processes, including proliferation, differentiation, apoptosis, tumorigenesis, and cell fate determination. This gene product is recognized by IgG antibodies isolated from breast cancer patients and appears to be a molecular marker associated with a wide range of human malignancies. Alternative transcriptional splice variants encoding different isoforms have been characterized.