Analysis of AVPR1B Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0806-LGZ)

Introduction

Official Full Name: arginine vasopressin receptor 1B<br />Also known as: V1bR; VPR3; AVPR3<br />The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.