Unlock Exclusive Discounts & Flash Sales! Click Here to Join the Deals on Every Wednesday!
Official Full Name: complement component 4 binding protein alpha
Also known as: PRP; C4BP
This gene encodes a member of a protein superfamily consisting mainly of short consensus repeats arranged in tandem of approximately 60 amino acids. In addition to a unique β-chain, seven identical α-chains encoded by this gene assemble into the major subtype of C4B-binding protein, a multimeric protein that controls the activation of the complement cascade through the classical pathway. The genes encoding the α- and β-chains are located adjacent to each other in the complement activation regulatory gene cluster on human chromosome 1. Two pseudogenes of this gene were also found in the cluster.