Analysis of CA14 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0817-LGZ)

Introduction

Official Full Name: carbonic anhydrase 14<br />Also known as: CAXiV<br />Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They exhibit wide diversity in tissue distribution and subcellular localization. CA XIV is predicted to be a type I membrane protein with the highest sequence similarity to the other transmembrane CA isoform, CA XII; however, they have different tissue-specific expression patterns and thus may exert different physiological roles.