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Official Full Name: chromatin target of PRMT1
Also known as: FOP; SRAG; SRAG-3; SRAG-5; pp7704; C1orf77; FL-SRAG; C10orf77
This gene encodes a small nucleoprotein characterized by an arginine- and glycine-rich region. This protein may play an important role in regulating fetal globin gene expression and activating estrogen-responsive genes. A recent study reported that this protein binds 5-hydroxymethylcytosine (5hmC) and associates with an arginine methyltransferase complex (methylosome), which promotes methylation of arginine 3 of histone H4 (H4R3) and activation of genes involved in glioblastom agenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.