Analysis of dendrimer biocides by UV-Vis Spectroscopy by UV-Vis Spectroscopy (CAT#: STEM-MB-0912-WXH)

Introduction

Dendrimers are novel highly-branched three-dimensional macromolecules that emanate from a central core. The advent of dendrimers represents a major breakthrough in synthetic chemistry. Dendrimers can be tailored to generate uniform or discrete functionalities and possess tunable inner cavities, surface moieties, sizes, molecular weights, and solvent interactions.
It has been shown that small quaternary ammonium compounds exert their antimicrobial action by disintegrating and disrupting the cell membrane, converting functional end groups of dendrimer to ammonium salts, dendrimer biocides can be synthesized. These dendrimer biocides have been shown to be more potent than their small molecule counterparts as they bear high local density active groups. Thus, dendrimer biocides may be very beneficial in terms of activity, reduced toxicity, localization
in specific organs and increased duration of action.