Analysis of DISP1 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0918-LGZ)

Introduction

Official Full Name: dispatched RND transporter family member 1
Also known as: DISPA
The patterns of cell proliferation and differentiation that lead to the normal development of embryonic structures often depend on the local production of secreted protein signals. Cells surrounding a particular signal source respond in a graded fashion according to the effective concentration of the signal, and this response produces a pattern of cell types that constitute the mature structure. A novel fragment polarity gene, called dispatcher, whose protein product is required for normal Hedgehog (Hh) signaling has been identified in Drosophila. This gene is one of the two human homologues of Drosophila, and based on the sequence identity with its mouse counterpart, the encoded protein may play an important role in the Hh patterning activity of early embryos.