Analysis of DYRK3 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0938-LGZ)

Introduction

Official Full Name: dual specificity tyrosine phosphorylation regulated kinase 3<br />Also known as: RED; REDK; DYRK5; hYAK3-2<br />The gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze the autophosphorylation of serine/threonine and tyrosine residues. Members of this family are structurally similar but differ in substrate specificity, suggesting their involvement in distinct cellular functions. The encoded protein has been shown to autophosphorylate tyrosine residues in vitro and catalyze the phosphorylation of histones H3 and H2B. Alternative splicing transcript variants encoding different isoforms have been identified.