Analysis of E-Selectin (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0159-LGZ)

Introduction

E-Selectin, also known as CD62E, endothelium - leukocyte adhesion molecule 2 (LECAM2), is a 115kDa glycoprotein, it is only expressed when activated by inflammatory cytokines (IL-1β or TNF-α) or endotoxins in endothelial cells. E-selectin on the cell surface mediates leukocyte attachment to the endothelium and thus plays an important role in local inflammatory responses. Monitoring serum sE-Selectin levels can provide more detailed insight into a number of pathological conditions such as cancer, infectious diseases, diabetes, and sepsis.