Analysis of FBXO38 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1854-LGZ)

Introduction

Official Full Name: F-box protein 38<br />Also known as: MOKA; Fbx38; HMN2D; SP329<br />This gene encodes a large protein that contains an F-box domain and may participate in protein ubiquitination. The encoded protein is a transcriptional co-activator of Krueppel-like factor 7 (Klf7). A heterozygous mutation in this gene was found in individuals with autosomal dominant distal hereditary motor neuronopathy type IID. There is a pseudogene for this gene on chromosome 4. Alternative splicing results in multiple transcript variants.