Analysis of FN1 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1511-LGZ)

Introduction

Official Full Name: fibronectin 1<br />Also known as: FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; SMDCF<br />This gene encodes fibronectin, a glycoprotein that exists as a soluble dimer in plasma and as a dimer or multimer on the cell surface and in the extracellular matrix. The encoded preproprotein undergoes proteolytic processing to generate the mature protein. Fibronectin is involved in cellular adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense and metastasis. The gene has three alternatively spliced regions with the potential to generate 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined.