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Official Full Name: geranylgeranyl diphosphate synthase 1
Also known as: GGPPS; MDHLO; GGPPS1; MUDHLOV
This gene is a member of the pentenyltransferase family and encodes a protein with geranyl diphosphate synthase activity. This enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-enoylation of proteins and the regulation of nuclear hormone receptors. Protein-coding and non-protein-coding transcriptional splice variants have been found for this gene.