Analysis of GIGYF2 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1539-LGZ)

Introduction

Official Full Name: GRB10 interacting GYF protein 2<br />Also known as: GYF2; PERQ2; PERQ3; PARK11; TNRC15<br />The gene contains CAG trinucleotide repeats and encodes a protein containing stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. The gene is located in the region of the chromosome associated with the inheritance of Parkinson's disease type 11, and mutations in this gene are thought to cause the disease. However, recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants.