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Official Full Name: gap junction protein alpha 8<br />Also known as: CAE; CAE1; CX50; CZP1; MP70; CTRCT1<br />This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.