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Official Full Name: glutamate ionotropic receptor NMDA type subunit 1
Also known as: NR1; MRD8; GluN1; NMDA1; DEE101; NDHMSD; NDHMSR; NMD-R1; NMDAR1
The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in synaptic plasticity, which is thought to underlie memory and learning. Cell-specific factors are thought to control the expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternative spliced transcript variants have been described.