Analysis of Guinea pig IL-6 by ELISA (CAT#: STEM-MB-1519-LGZ)

Introduction

Interleukin 6(IL-6) is a cytokine with both pro-inflammatory and anti-inflammatory properties. In humans, it is encoded by the IL-6 gene. During infection and after trauma, especially inflammation caused by burns or other tissue damage, IL-6 is secreted by T cells and macrophages to promote the immune response. Studies have shown that IL-6 is required to resist Streptococcus pneumoniae infection in mice, suggesting that IL-6 plays a role in the resistance to infection. IL-6 has been implicated in inflammatory and autoimmune disease progression in many diseases such as diabetes, atherosclerosis, depression, Alzheimer's disease, systemic lupus erythematosus, multiple myeloma, prostate cancer, Behcet's disease, and rheumatoid arthritis. Patients with advanced/metastatic cancer have higher levels of IL-6 in their blood.