Analysis of H2BC21 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1021-LGZ)

Introduction

Official Full Name: H2B clustered histone 21<br />Also known as: H2B; H2BE; H2BQ; GL105; H2B.1; H2BFQ; H2BGL105; H2B-GL105; HIST2H2BE<br />Histones are fundamental nuclear proteins responsible for the structure of eukaryotic chromosome fibers in the nucleosome. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, and about 146 bp of DNA are packaged in repeating units called nucleosomes. Linker histone H1 interacts with linker DNA between nucleosomes and plays a role in the compaction of chromatin into higher-order structures This gene encodes a replication-dependent histone that is a member of the H2B histone family and generates two transcripts through the use of a conserved stem-loop termination motif and a polyA addition motif. The protein has antibacterial and antifungal activity.