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C-X-C motif chemokine 11 (CXCL11), also known as interferon-induced T cell alpha chemokine (I-TAC), is a small molecular weight cytokine in the CXC chemokine family. Its gene is located on human chromosome 4 like many other CXC chemokine family members. It is highly expressed in peripheral blood leukocytes, pancreas, and liver, moderately expressed in thymus, spleen, and lung, and lowly expressed in small intestine, placenta, and prostate tissue.