Analysis of Ikaros (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0289-LGZ)

Introduction

Ikaros is one of the giant transcription factors that regulate the developmental process of the lymphatic system. During the development of the hematopoietic system, the Ikaros family not only exhibits its regulatory function by regulating the expression of target genes, but also interacts with the heterochromatin remodeling complex containing inert genes to regulate its transcriptional activity. And through the evolutionary analysis of Ikaros family members of different species, it is found that they are highly conserved and may be related to the origin of the adaptive immune system.