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Official Full Name: inhibitor of nuclear factor kappa B kinase subunit epsilon
Also known as: IKKE; IKKI; IKK-E; IKK-i
IKBKE is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines.