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Analysis of IL-17A/F (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0308-LGZ)

Introduction

IL-17A and IL-17F are important members of the IL-17 family of cytokines that regulate innate and adaptive immunity. IL-17A is associated with chronic inflammatory and autoimmune diseases, and anti-IL-17A antibodies have shown significant clinical efficacy in patients with psoriasis and psoriatic arthritis. IL-17A and IL-17F are homodimeric cytokines that also form IL-17A/F heterodimers, and their precise roles in health and disease remain elusive.




Principle

Detection Technique: MSD Hypersensitive Multi-Factor Electrochemiluminescence
Capture Antibody: Mouse Monoclonal
Detection Antibody: Mouse Monoclonal
Recombinant Standards: Expressed in Chinese hamster cell line

Applications

Cytokines & Chemokines, Immunology/Inflammation

Procedure

1. Coat the capture antibody on the well plate.
2. Add samples/calibrators.
3. Add detection antibody.
4. Read the plate and analyze the data.

Materials

• Sample Type: Serum, Plasma, Cell Culture Supernatant, Urine
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