Analysis of Interaction between Diosmetin and serum albumin by UV-Vis Spectroscopy (CAT#: STEM-MB-0934-WXH)

Introduction

Diosmetin is an O-methylated flavone and the aglycone part of the flavonoid glycosides diosmin that occurs naturally in citrus fruits. Pharmacologically, diosmetin is reported to exhibit anticancer, antimicrobial, antioxidant, oestrogenic and anti-inflamatory activities. It also acts as a weak TrkB receptor agonist.
Serum albumins (SAs), the most abundant proteins in blood plasma, play important roles in the transport and deposition of a variety of endogenous and exogenous substances including fatty acids, amino acids, metals, and pharmaceuticals in blood. The binding of toxins to serum albumins may have physiological importance, because they controls their free, active concentrations and affect the duration and intensity of their effects.