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Official Full Name: keratin 19
Also known as: K19; CK19; K1CS
The protein encoded by this gene is a member of the keratin family. Keratin is an intermediate filament protein responsible for the structural integrity of epithelial cells and is subdivided into cytokeratin and hair keratin. Type I cytokeratins consist of acidic proteins arranged in pairs of heterokeratin chains. Unlike related family members, this smallest known acidic cytokeratin does not pair with basal cytokeratins in epithelial cells. It is specifically expressed in the periderm, the transient superficial layer that wraps the developing epidermis. Type I cytokeratins accumulate in a region of chromosome 17q12-q21.