Analysis of Leptin (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0385-LGZ)

Introduction

Leptin is a hormone that helps regulate appetite by signaling hunger satisfaction (satiety). Leptin is produced primarily by fat cells (adipocytes) and to a lesser degree by other tissues, including the placenta in pregnant women. It is transported in the blood receptors in the hypothalamus in the brain. When sufficient food has been consumed, it tells the body that it is no longer hungry. Leptin deficiency or resistance can result in profound obesity, diabetes, and infertility in humans. Since its discovery, our understanding of leptin's biological functions has expanded from anti-obesity to broad effects on reproduction, hematopoiesis, angiogenesis, blood pressure, bone mass, lymphoid organ homeostasis, and T lymphocyte systems.