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Official Full Name: MAPK activated protein kinase 2<br />Also known as: MK2; MK-2; MAPKAP-K2<br />This gene encodes a member of the serine/threonine protein kinase family. This kinase is regulated by direct phosphorylation of p38 MAP kinase. Along with p38 MAP kinase, this kinase is involved in many cellular processes, including stress and inflammatory responses, nuclear export, regulation of gene expression, and cell proliferation. Heat shock protein HSP27 is one of the substrates of this kinase in vivo. Two transcript variants of this gene have been found encoding two different isoforms.