Analysis of MET (soluble) (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0414-LGZ)

Introduction

c-Met (cellular-mesenchymal to epithelial transition factor) gene, also known as MET gene, is a proto-oncogene, transmembrane receptor encoding hepatocyte growth factor, c-Met possesses tyrosine kinase (TKs) activity, which is the only known high affinity receptor for hepatocyte growth factor. Activated c-Met binds to hepatocyte growth factor (HGF) to regulate the proliferation, differentiation and invasion activities of various tissues and cells in the body. Once the constituted HGF/c-Met signaling pathway is abnormally activated, it will promote the occurrence, development and metastasis of various tumors.