Analysis of MTUS1 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1912-LGZ)

Introduction

Official Full Name: microtubule associated scaffold protein 1<br />Also known as: ATBP; ATIP; ICIS; MP44; ATIP3; MTSG1<br />This gene encodes a protein that contains a C-terminal domain capable of interacting with the angiotensin II (AT2) receptor and a large coiled-coil region that allows dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and participates in the AT2 signaling pathway. Other variants may encode nuclear or transmembrane proteins, but it has not been determined whether they are also involved in AT2 signaling.