Analysis of Neurofilament H (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0456-LGZ)

Introduction

Neurofilament H, also known as 200 kDa neurofilament protein, and neurofilament L, M are three intermediate fiber proteins of neurofilament. Neurofilament H is involved in the maintenance of neuronal caliber and may play a role in intracellular transport. Neurofilament H is used as a biomarker of neuronal damage, and mutations in this gene are associated with susceptibility to amyotrophic lateral sclerosis. The human neurofilament H amino acid sequence is 75% identical to the mouse and rat neurofilament H sequences.