Analysis of NLRP10 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-2300-LGZ)

Introduction

Official Full Name: NLR family pyrin domain containing 10<br />Also known as: NOD8; PAN5; PYNOD; NALP10; CLR11.1<br />Members of the NALP protein family generally contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). Although the protein encoded by this gene lacks the LRR region, it belongs to the NALP protein family. This protein may play a regulatory role in the innate immune system. This protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments have shown that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.