Analysis of OTOA Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-2468-LGZ)

Introduction

Official Full Name: otoancorin<br />Also known as: CT108; DFNB22<br />The protein encoded by this gene is expressed specifically in the inner ear, at the interface between the apical surface of the inner ear sensory epithelium and its overlying decellularized gel. It has been suggested that this protein is involved in the attachment of decellularized gels of the inner ear to the apical surface of underlying nonsensory cells. Mutations in this gene are associated with autosomal recessive deafness type 22 (DFNB22). Alternative splice transcript variants of this gene have been found to encode distinct isoforms.