Analysis of PEX14 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1371-LGZ)

Introduction

Official Full Name: peroxisomal biogenesis factor 14<br />Also known as: NAPP2; PBD13A; Pex14p; dJ734G22.2<br />This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.