Analysis of PSGL-1 (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0509-LGZ)

Introduction

P-Selectin Glycoprotein Ligand 1 is also called SELPLG or CD162. SELPLG encodes PSGL-1, a high-affinity antireceptor for p-selectin on myeloid cells and stimulated T lymphocytes. Thus, they play a key role in binding these cells to activated platelets or endothelial cells expressing P-selective proteins. P-selectin glycoprotein ligand 1 (PSGL-1) is a glycoprotein found on white blood cells and endothelial cells that binds to P-selectin (P for platelets) and is a member of the selectin family, including e-selectin (endothelial cells) and L-selectin (white blood cells). Selectins are part of a broader family of cell adhesion molecules. PSGL-1 binds to all three members of the family, but binds best to P-selectin (highest affinity).