Analysis of RBBP5 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0349-LGZ)

Introduction

Official Full Name: RB binding protein 5, histone lysine methyltransferase complex subunit<br />Also known as: RBQ3; SWD1<br />This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.