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Official Full Name: regulator of G protein signaling 13
The protein encoded by this gene is a member of the Regulator of G-protein Signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS protein accelerates G protein α subunit GTPase activity, thereby driving G protein into an inactive GDP binding form, This negatively regulates G protein signaling. RGS proteins are involved in the fine-tuning of various cellular events in response to G protein-coupled receptor activation. However, the biological function of this gene is unknown. There are two transcript variants encoding the same isoform.