Analysis of S100A5 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0331-LGZ)

Introduction

Official Full Name: S100 calcium binding protein A5<br />Also known as: S100D<br />The protein encoded by this gene is a member of the S100 protein family, which contains two EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a variety of cells and are involved in the regulation of many cellular processes, such as cell cycle progression and differentiation. The S100 gene includes at least 13 members, which are located on chromosome 1q21. The Ca2+ affinity of this protein is 20-100 times higher than other S100 proteins studied under the same conditions. The protein also binds Zn2+ and Cu2+, Cu2+ strongly weakens the binding of Ca2+. This protein is expressed in a very limited area of the adult brain.