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Visceral fat-specific serine protease inhibitor (Vaspin, also known as Serpin A12), a 47kDa protein with 415 amino acids, belongs to the serine protease inhibitor (serpin) family and is also an interesting new adipocyte cytokine. The expression of Serpin A12 in abdominal adipose tissue is adipocyte-specific, and with the increase of visceral adipose tissue mass, the expression of Serpin A12 in subcutaneous adipose tissue will also decrease.