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Solid lipid nanoparticles (SLN) are nanocarriers in the 10–1000 nm range of a solid core, containing both hydrophilic and hydrophobic active pharmaceutical ingredients. SLNs are composed of well-tolerated and biodegradable solid lipids such as mono-, di-, and triglycerides, fatty acids, waxes, and steroids, as well as lipophilic and hydrophilic emulsifying agents. This composition of biocompatible molecules makes SLNs one of the most successful options for the administration of drugs with different routes of administration.