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Official Full Name: serine peptidase inhibitor Kazal type 1<br />Also known as: TCP; PCTT; PSTI; TATI; Spink3<br />The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis.