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Official Full Name: SUFU negative regulator of hedgehog signaling<br />Also known as: BCNS2; SUFUH; JBTS32; SUFUXL; PRO1280<br />The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.