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Official Full Name: synaptotagmin 8
This gene encodes a member of the synaptophysin family. Synaptomin is a membrane protein that plays an important role in neurotransmission and hormone secretion, both of which are involved in the regulation of extracellular secretion. Expression of the encoded protein in human islets is linked to the activity of the insulin gene promoters, which are located hundreds of bases away on the same chromosome. This association would link the response to glucose to insulin secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.