Analysis of TAF5L Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0300-LGZ)

Introduction

Official Full Name: TATA-box binding protein associated factor 5 like<br />Also known as: PAF65B<br />The product of this gene belongs to the WD-repeat TAF5 protein family. This gene encodes a protein that is part of the PCAF histone acetylase complex. The PCAF histone acetylase complex consists of more than 20 polypeptides, some of which are TAFs, and are required for myogenic transcription and differentiation. TAFs may be involved in basal transcription, acting as coactivators, functioning in promoter recognition or modifying general transcription factors to facilitate complex assembly and transcription initiation. The encoded protein is structurally similar to TAF5, one of the histone-like TAFs. Alternative splicing transcript variants encoding different isoforms of this gene have been identified.