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Official Full Name: taste 1 receptor member 1
Also known as: TR1; T1R1; GM148; GPR70
The protein encoded by this gene is a G protein-coupled receptor, which is a component of the heterodimeric amino acid taste receptor T1R1+3. T1R1+3 receptors respond to l-amino acids but not to d-enantiomers or other compounds. Most amino acids considered sweet activate T1R1+3, and this activation is strictly dependent on intact T1R1+3 heterodimers. Multiple transcript variants of this gene have been found encoding different isoforms.