Analysis of Tau (pT181) (Non-human primate) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0561-LGZ)

Introduction

Tau protein is a major component of neurofibrillary tangles and a marker for a range of neurodegenerative diseases, including Alzheimer's disease (AD). There are 6 isoforms of tau protein, and these 6 isoforms are often present in the PHF of AD in a hyperphosphorylated state.

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Principle Applications Procedure Materials Notes Related Products

Principle

Detection Technique: MSD Hypersensitive Multi-Factor Electrochemiluminescence
Capture Antibody: Mouse monoclonal
Detection Antibody: Mouse monoclonal
Recombinant Standards: Expressed in Human cell line

Applications

Neurobiology/Neurodegeneration, Alzheimer’s Disease

Procedure

1. Coat the capture antibody on the well plate.
2. Add samples/calibrators.
3. Add detection antibody.
4. Read the plate and analyze the data.

Materials

• Sample Type: Serum, Plasma, Cell Culture Supernatant

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