Unlock Exclusive Discounts & Flash Sales! Click Here to Join the Deals on Every Wednesday!
Also known as: BBP; 53BP2; ASPP2; P53BP2; PPP1R13A
This gene encodes a member of the ASPP (pro-apoptotic protein) family of p53-interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It localizes in the perinuclear region of the cytoplasm and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.