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Official Full Name: tripartite motif containing 46
Also known as: GENEY; TRIFIC
This gene encodes a tripartite motif (TRIM) family protein. The TRIM motif includes a zinc-binding domain, a RING finger region, a B-box motif, and a coil domain. TRIM46 has been reported to be involved in the proliferation of various cancer cells, including lung and breast cancer. It has also been shown to control neuronal polarity and axon specification through the formation of uniform microtubule bundles in axons.