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Official Full Name: urotensin 2<br />Also known as: UII; U-II; UCN2; PRO1068<br />This gene encodes a mature peptide, an active cyclic heptapeptide that is absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is only expressed in brain tissue. Despite the similar gene family name, this gene is not homologous to urocortin, a member of the sovagine/corticotropin-releasing factor/urotensin I family. Most proteins are cleaved into mature peptides. Transcript variants encoding different preproprotein isoforms have been described for this gene.