Anavo® Hybrid and High-Strength Silica UHPLC Columns XP (Hybrid Particle Technology) Anavo XP hybrid particle chromatographic packing sets the industry standard for chromatographic versatility, chemical resistance, and mechanical stability. XP columns enhance retention and selectivity for acidic, basic, and neutral analytes under extreme pH and temperature conditions. The XP hybrid chromatographic packing exhibits exceptional stability within a pH range of 1-12, offering high column efficiency and excellent peak symmetry. PHS XP (Hybrid Surface Charged Particle Technology) Anavo PHS XP surface-charged hybrid particle packing combines the excellent properties of XP particles with enhanced chromatographic selectivity and superior peak shape in low ionic strength mobile phases. The optimized surface charge, porosity, and bonded phase make it an ideal choice for rapid method development. HSS (High-Strength Silica Particle Technology) Anavo HSS high-strength silica particle packing offers higher silane affinity (100% silica), providing significant advantages in chromatographic work, including improved retention of polar compounds and varied selectivity. HSS particles possess high mechanical strength, capable of withstanding pressures up to 18,000 psi (1240 bar).