Bioavailability Study Service Based on LC-MS/MS

STEMart offers comprehensive Bioavailability Study Services using LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry), a cutting-edge technology that enables precise and sensitive quantification of drug concentrations in biological matrices. In our laboratory, LC-MS/MS is essential for conducting bioavailability studies, allowing us to determine the fraction of an administered drug that reaches the systemic circulation. This technology is critical for drug development, as it provides accurate data on drug absorption, supporting informed decisions during clinical trials and regulatory submissions.

LC-MS/MS combines the separation power of liquid chromatography with the detection capabilities of tandem mass spectrometry, allowing for the accurate analysis of drug compounds in complex biological samples such as blood, plasma, and urine. The technology operates by separating compounds based on their physical and chemical properties, followed by mass analysis, where ions are fragmented and detected to provide detailed structural information. LC-MS/MS is widely used in bioavailability studies to evaluate drug absorption, compare different formulations, and optimize dosing regimens.

Leveraging our expertise in bioanalysis and the advanced capabilities of LC-MS/MS, STEMart offers a range of bioavailability study services designed to meet the specific needs of our clients. From comparative bioavailability studies to first-pass metabolism analysis, our services provide the high-quality data necessary to advance your drug development projects.

What We Offer

• Comparative Bioavailability Studies

We conduct detailed comparative studies to evaluate the bioavailability of different drug formulations, helping to identify the most effective delivery method.

• First-Pass Metabolism Analysis

Our service includes analysis of first-pass metabolism, providing insights into the fraction of drug absorbed and metabolized before reaching systemic circulation.

• Absolute and Relative Bioavailability Studies

We offer both absolute and relative bioavailability studies, delivering precise quantification of drug absorption and comparing different administration routes.

• Formulation Optimization

Using LC-MS/MS, we help optimize drug formulations by analyzing bioavailability data, ensuring that your product achieves the desired therapeutic effect.

Why Choose Us

• High Sensitivity and Accuracy

Our LC-MS/MS system offers high sensitivity and accuracy, ensuring reliable quantification of drugs and metabolites in complex biological samples.

• Comprehensive Bioavailability Analysis

We provide thorough bioavailability analysis, covering all aspects from absorption to metabolism, delivering critical data for drug development.

• Regulatory Compliance

Our bioavailability studies are conducted following regulatory guidelines, ensuring that your data meets the requirements for drug approval.

Our Equipment

LC-MS/MS

This advanced system combines liquid chromatography with tandem mass spectrometry, offering precise separation and analysis of drug compounds, crucial for accurate bioavailability studies.

Triple Quadrupole MS

Complementing our LC-MS/MS, this instrument delivers targeted quantification of specific drugs and metabolites, ensuring accurate and reproducible results in bioavailability studies.

Nano-LC-MS/MS

This nano-scale liquid chromatography system coupled with tandem mass spectrometry offers superior sensitivity, making it ideal for analyzing low-abundance compounds in bioavailability studies.

STEMart provides high-quality mass spectrometry services tailored to meet the specific needs of our clients. Our experienced specialists use advanced equipment and follow strict quality control measures to ensure accurate and reliable results. Contact us to learn more about our mass spectrometry services and how we can help you achieve your research goals.